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Journal Autophagy & cellular renewal
Discovery

PRRSV NSP2 hijacks host lipophagy via a LIPE-PNPLA2-AMPK-MTOR axis to promote viral replication

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Source: [pubmed](https://pubmed.ncbi.nlm.nih.gov/42200529/)

Authors: Zhu Z, Lin Q, Zhang X, Zhang M, Yan Y

Venue: Autophagy · 2026 May 27

AI relevance (4/5): Directly investigates AMPK-MTOR axis in lipophagy (selective autophagy), core mechanism named in brief, but viral context limits generalizability.

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Published 2026-05-29 · Last kit-update 2026-05-28