Bionoia Where life meets thought ⌕
Back to Journal
Journal › Sleep biology
Discovery

Melatonin suppresses ILC2-driven airway hyperreactivity via glutathione-dependent metabolic reprogramming

Read original paper

Source: [pubmed](https://pubmed.ncbi.nlm.nih.gov/42199420/)

Authors: Cain J, Hurrell BP, Shen S, Speliakos P, Akbari O

Venue: Front Immunol · 2026

AI relevance (4/5): Melatonin's immune-metabolic mechanism directly matches brief's inclusion of melatonin physiology beyond timing; likely animal/in-vitro study.

--- *Draft auto-created from Suggestions queue. Polish the body, set is_real=true when verified, and publish via `INSERT INTO bionoia_published` when ready for /public/.*

Related articles in this corpus

Parallel
Sleep and Performance
Both articles address sleep-related biology (melatonin/circadian function) and physiological outcomes, but operate in distinct mechanistic domains (cognitive performance vs. immune-metabolic airway regulation) with no direct causal or evidence relationship.
Parallel
Stress during the first 1,000 days of life in humans, when everything begins
Both address stress-related physiological mechanisms during critical developmental periods, but operate at different biological levels (developmental stress timing vs. immune-metabolic regulation) without direct causal overlap.
Parallel
Effects of chronic jetlag on high-fat and high-fructose diet induced renal injury in mice
Both investigate melatonin's protective role in disease models (renal injury and airway hyperreactivity) through metabolic and immunological mechanisms, but address distinct organ systems and pathways without direct experimental overlap.
Parallel
Research on the Efficacy and Safety of Targeted Suprachiasmatic Nucleus Electrical Stimulation for Improving Metabolic Disorders in Patients With Stable Bipolar Disorder Comorbid With Obesity
Both articles involve circadian/metabolic regulation mechanisms (suprachiasmatic nucleus control and melatonin-driven metabolic reprogramming) but target distinct diseases (bipolar disorder/obesity vs. airway hyperreactivity) with no direct mechanistic overlap.
Published 2026-05-29 · Last kit-update 2026-05-28