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All published Bionoia articles. Filter by topic, evidence tier, study type, or tag.
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2 articles of 156
The sepsis-permeability feedback loop
HypothesisMucosa · Mechanisms of dysfunction · mechanism_review
"Leaky gut → sepsis" is not a one-way mechanism. It is a self-reinforcing cycle.
Both leaky gut (barrier defect at intestinal surface) and gut dysbiosis are intrinsic to sepsis. W…
The glycocalyx and heparan sulfate / syndecan-1
HypothesisMucosa · Architecture · mechanism_review
A third barrier system, often overlooked in clinical discussion: the glycocalyx layer on the basolateral side of enterocytes, primarily based on heparan sulfate proteoglycans (espe…