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All published Bionoia articles. Filter by topic, evidence tier, study type, or tag.

Topic
Autophagy & cellular renewal 16Chronic inflammation 5Microbiome ecology 21Mitochondrial biology 22Mucosa 55Resolution biology 4Sleep biology 18Stress biology 15
Evidence tier
Evidence 3Hypothesis 65Speculation 30
Study type
Human observational 1Mixed 2Animal 1Mechanism review 17
Tags
mechanism 19barrier 17microbiome 14inflammation 14marker 14intervention 6supplement 6technique 3resolution 2ernæring 2omega-3 2goblet cells 2dysbiosis 2sepsis 2eicosanoids 1
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11 articles of 156

Dexmedetomidine attenuates LPS-induced acute lung injury via activation of mitochondrial autophagy
Speculation
Mitochondrial biology · Discovery ·
**Source:** openalex · Origin: **CN** · Huaixin Xing, Yan Ma, Xiangzhen Min, Yingui Sun, Guanrong Li · European journal of medical research · 2026-05-26 **URL:** https://d…
Impact of aldehyde dehydrogenase 2 deficiency on tissue-specific mitochondrial metabolism in aging mice
Speculation
Mitochondrial biology · Discovery ·
**Source:** openalex · Origin: **FR** · Márcio A. C. Ribeiro, Vanessa Morais Lima, Thiago N. Menezes, Wenjin Yang, Juliane C. Campos · bioRxiv (Cold Spring Harbor Laboratory)…
Semaglutide targets the Isg15-FUNDC1 axis: suppressing IFN-β overactivation and attenuating blood-brain barrier injury in diabetic intracerebral hemorrhage
Speculation
Mitochondrial biology · Discovery ·
**Source:** europepmc · Origin: **CN** · Wang Y, Kuang B, Chen Y, Zou W, Zheng L, Zhang B, Shang T, Xu C, Xu Q, Li H, Hu Y, Zhao K, Kuang H. · Journal of neuroinflammation ·…
SIRT5-dependent desuccinylation licenses UBR5-mediated degradation of TAMM41 to regulate mitochondrial metabolism in lung adenocarcinoma
Speculation
Mitochondrial biology · Discovery ·
**Source:** europepmc · Origin: **CN** · Yuan H, Hu W, Lv X, Cao Y, Hu K, Li Y, Chen Z, Yang J, Wang Y, Zhao J, Xu C. · Biology direct · 2026-05-25 **URL:** https://pubmed…
Exercise hormone irisin alleviates rheumatoid arthritis by removing dysfunctional mitochondria
Speculation
Mitochondrial biology · Discovery ·
**Source:** europepmc · Origin: **CN** · Wu Y, Fu T, Teng Y, Pan Y, Li L, Feng Y, Lin J. · Autophagy · 2026-05-25 **URL:** https://pubmed.ncbi.nlm.nih.gov/42186185/ **AI …
Diphlorethohydroxycarmalol isolated from <i>Ishige okamurae</i> improves age-related muscle dysfunction by Ca<sup>2+</sup>-dependent response <i>via</i> the SirT1/PGC-1α pathway <i>in vitro</i> and <i>i
Speculation
Mitochondrial biology · Discovery ·
**Source:** europepmc · Origin: **KR** · Wang X, Kim CY, Je JG, Roh YJ, Yang F, Yang HW, Jeon YJ. · Food & function · 2026-05-26 **URL:** https://pubmed.ncbi.nlm.nih.gov/4…
Cardiomyocyte BMAL1 deficiency worsens obesity-related cardiomyopathy with heightened PINK1/Parkin-linked mitophagy and mitochondrial dysfunction
Speculation
Mitochondrial biology · Discovery ·
**Source:** europepmc · Origin: **CN** · Liu T, Fan X, Zhang N, Wang Y, Qian Z, Hou X, Zhang H, Zou J. · Journal of biomedical research · 2026-05-25 **URL:** https://pubme…
Heterogeneous Mitochondrial Gene Expression in SH-SY5Y Cells Following ERRa and ERRy Depletion Reveals Divergent Stress Responses
Speculation
Mitochondrial biology · Discovery ·
**Source:** europepmc · Mandel AR. · Research Square · 2026-05-25 **URL:** https://europepmc.org/article/PPR/PPR1237947 **AI rationale (4/5, tier: preliminary):** Mechanism…
Hirudin Promotes Peripheral Nerve Repair by Enhancing Mitophagy to Suppress NLRP3 Inflammasome Activation
Speculation
Mitochondrial biology · Discovery ·
**Source:** europepmc · Yan R, Zhe Z, Zhang J, Lin T, Xiao S, Liu H, Mao H, Cooper T, Alqadhi S, Li B, Wu L. · Research Square · 2026-05-25 **URL:** https://europepmc.org/ar…
Inhibition of Mitochondrial Respiration Fragments ER Architecture and Remodels Organelle Contact Sites, as Revealed by FIB-SEM
Speculation
Mitochondrial biology · Discovery ·
**Source:** europepmc · Dlaskova A, Bazila B, Krepelka P, Victor RC, Jhala DJ, Jezek P. · bioRxiv · 2026-05-25 **URL:** https://europepmc.org/article/PPR/PPR1238456 **AI ra…
Semaglutide targets the Isg15-FUNDC1 axis: suppressing IFN-β overactivation and attenuating blood-brain barrier injury in diabetic intracerebral hemorrhage
Speculation
Mitochondrial biology · Discovery ·
**Source:** openalex · Origin: **CN** · Yue Wang, Binglin Kuang, Chen Yangwen, Wei Zou, Lei Zheng · Journal of Neuroinflammation · 2026-05-25 **URL:** https://doi.org/10.1…