Microbiome ecology
The gut as ecosystem — species, diversity, and dynamics
The gut microbiome is the largest single influence on human physiology that we still understand only partially. This topic curates the evidence — colonisation dynamics, dysbiosis, FMT engraftment, keystone species, antibiotic resilience — with the same citation rigor as the…
Microbiota remodeling after bariatric surgery: Procedure-specific dynamics and metabolic implications
Bariatric surgery is recognized as the most effective surgical strategy for achieving sustained weight loss and improving metabolic disorders in patients with severe obesity. Beyond anatomical restriction and caloric malabsorption, increasing evidence suggests that surgery-induced remodeling of the gut microbiota plays a critical role in mediating postoperative metabolic…
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16 articles in Microbiome ecology tagged Hypothesis, sorted by dateMediterranean Diet and Weight Loss: Targeting the Bile Acid/Gut Microbiome Axis to Reduce Colorectal Cancer
A Mediterranean Diet (MedDiet), a largely plant-based dietary pattern, is relevant to CRC prevention and microbial production of anti-cancer metabolites in observational studies.…
Read article →Gut Microbiome in AP Naive
Antipsychotic (AP) medications are currently the cornerstone of treatment for schizophrenia (SCZ), with off-label prescription rapidly increasing in youth, with an established…
Read article →Influence of Probiotics on Early Gut Microbial Colonization
The goal of this clinical trial is to learn whether daily probiotic drops plus vitamin D3 can improve early gut microbiome colonization in healthy infants born by C-section. It…
Read article →The Effect of OptiFibre Dietary Fiber on Carbohydrate Metabolism and Intestinal Microbiota Metabolism in Patients With Type 2 Diabetes Mellitus
The goal of this clinical trial is to to study the effect of Optifiber PHGG on carbohydrate metabolism in patients with type 2 diabetes mellitus. The main questions it aims to…
Read article →Antimicrobial resistance and the human gut microbiome-a food safety perspective
The gastrointestinal environment is where the resident gut microbiome encounters foodborne microorganisms, antimicrobial resistance genes (ARGs), and bioactive substances from…
Read article →Integrated gut microbiota and metabolome signatures revealed by deep metagenomic sequencing in post-stroke cognitive impairment with type 2 diabetes
Post-stroke cognitive impairment (PSCI) is significantly exacerbated in individuals with type 2 diabetes mellitus (T2DM), yet the underlying gut microbial and metabolic mechanisms…
Read article →Gut Microbiota Regulates Systemic Inflammatory Response and Compensatory Anti-Inflammatory Response Syndromes by Targeting PF4<sup>+</sup> Macrophages in Acute Pancreatitis
Acute pancreatitis (AP) begins with pancreatic local inflammation, leading to the onset of systemic inflammatory response syndrome (SIRS), followed by compensatory…
Read article →Enterotype-specific microbial biomarkers of immune checkpoint inhibitor response revealed by large-scale integrated metagenomic analysis
The gut microbiota appears to play a critical role in modulating antitumor immune responses and influencing the efficacy of cancer immunotherapy drugs such as immune checkpoint…
Read article →Effects of processed low-protein brown rice on patients with chronic kidney disease
Alterations in gut microbiota are prevalent in patients with chronic kidney disease (CKD) and are associated with pathogenic phenotypes, including the progression of kidney damage…
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