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Microbiome ecology

The gut as ecosystem — species, diversity, and dynamics
The gut microbiome is the largest single influence on human physiology that we still understand only partially. This topic curates the evidence — colonisation dynamics, dysbiosis, FMT engraftment, keystone species, antibiotic resilience — with the same citation rigor as the…

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HypothesisMicrobiome ecology5 days ago

Microbiota remodeling after bariatric surgery: Procedure-specific dynamics and metabolic implications

Bariatric surgery is recognized as the most effective surgical strategy for achieving sustained weight loss and improving metabolic disorders in patients with severe obesity. Beyond anatomical restriction and caloric malabsorption, increasing evidence suggests that surgery-induced remodeling of the gut microbiota plays a critical role in mediating postoperative metabolic…

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Latest research

16 articles in Microbiome ecology tagged Hypothesis, sorted by date
HypothesisMicrobiome ecology5 days ago

Mediterranean Diet and Weight Loss: Targeting the Bile Acid/Gut Microbiome Axis to Reduce Colorectal Cancer

A Mediterranean Diet (MedDiet), a largely plant-based dietary pattern, is relevant to CRC prevention and microbial production of anti-cancer metabolites in observational studies.…

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HypothesisMicrobiome ecology5 days ago

Gut Microbiome in AP Naive

Antipsychotic (AP) medications are currently the cornerstone of treatment for schizophrenia (SCZ), with off-label prescription rapidly increasing in youth, with an established…

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HypothesisMicrobiome ecology5 days ago

Influence of Probiotics on Early Gut Microbial Colonization

The goal of this clinical trial is to learn whether daily probiotic drops plus vitamin D3 can improve early gut microbiome colonization in healthy infants born by C-section. It…

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HypothesisMicrobiome ecology5 days ago

The Effect of OptiFibre Dietary Fiber on Carbohydrate Metabolism and Intestinal Microbiota Metabolism in Patients With Type 2 Diabetes Mellitus

The goal of this clinical trial is to to study the effect of Optifiber PHGG on carbohydrate metabolism in patients with type 2 diabetes mellitus. The main questions it aims to…

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HypothesisMicrobiome ecology5 days ago

Antimicrobial resistance and the human gut microbiome-a food safety perspective

The gastrointestinal environment is where the resident gut microbiome encounters foodborne microorganisms, antimicrobial resistance genes (ARGs), and bioactive substances from…

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HypothesisMicrobiome ecology5 days ago

Integrated gut microbiota and metabolome signatures revealed by deep metagenomic sequencing in post-stroke cognitive impairment with type 2 diabetes

Post-stroke cognitive impairment (PSCI) is significantly exacerbated in individuals with type 2 diabetes mellitus (T2DM), yet the underlying gut microbial and metabolic mechanisms…

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HypothesisMicrobiome ecology5 days ago

Gut Microbiota Regulates Systemic Inflammatory Response and Compensatory Anti-Inflammatory Response Syndromes by Targeting PF4<sup>+</sup> Macrophages in Acute Pancreatitis

Acute pancreatitis (AP) begins with pancreatic local inflammation, leading to the onset of systemic inflammatory response syndrome (SIRS), followed by compensatory…

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HypothesisMicrobiome ecology5 days ago

Enterotype-specific microbial biomarkers of immune checkpoint inhibitor response revealed by large-scale integrated metagenomic analysis

The gut microbiota appears to play a critical role in modulating antitumor immune responses and influencing the efficacy of cancer immunotherapy drugs such as immune checkpoint…

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HypothesisMicrobiome ecology5 days ago

Effects of processed low-protein brown rice on patients with chronic kidney disease

Alterations in gut microbiota are prevalent in patients with chronic kidney disease (CKD) and are associated with pathogenic phenotypes, including the progression of kidney damage…

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