Chronic inflammation
Inflammaging — when the alarm never stops
Acute inflammation is a feature, chronic inflammation is a bug. This topic curates the evidence on the slow-burn inflammation that links obesity to cancer, aging to dementia, and stress to autoimmunity.
Effects of Tirzepatide on Weight Loss and Chronic Inflammation in People With HIV
This is a prospective cohort study of 12 overweight (with one or more weight-related condition) or obese adults with well controlled HIV-1 on antiretroviral therapy (ART). An initial dose of tirzepatide (TZP) 2.5 mg subcutaneous (SQ) once weekly will be given, escalated by 2.5 mg at 4-week intervals to a final dose of 7.5mg. The investigators will collect the following…
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