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Sleep biology

Why we sleep — circadian rhythms and the glymphatic system
Sleep is when the brain self-cleans, the immune system consolidates, and memory is encoded. This topic curates the evidence on why sleep matters — biologically, not just behaviourally.

AllEvidenceHypothesisSpeculationPractice
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HypothesisSleep biology5 days ago

Obstructive Sleep Apnoea and Difficult Asthma (OSADA)

The OSADA (Obstructive Sleep Apnoea in Difficult Asthma) trial is an open-label, randomized control trial investigating the impact of diagnosing and treating obstructive sleep apnoea (OSA) on a asthma control in patients with difficult-to-control asthma. Participants will undergo home-based sleep studies to assess for OSA and are then allocated to one of three arms: 1)…

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Latest research

6 articles in Sleep biology tagged Hypothesis, sorted by date
HypothesisSleep biology5 days ago

Neurocognitive and Health Impact of Sleep Apnea in Elderly Veterans With Comorbid COPD

Cognitive dysfunction in the aging Veteran population is a growing health concern in the Veterans Health System. It is not known whether OSA coexisting with COPD will enhance the…

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HypothesisSleep biology5 days ago

Population Based Lighting Study on Older Adults

The ENLIGHTENme project aims at collecting evidence about the impact of outdoor and indoor lighting on human health and wellbeing through the development and testing of innovative…

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HypothesisSleep biologyMay 26

dlmoR: An open-source R package for the dim-light melatonin onset (DLMO) hockey-stick method

The dim-light melatonin onset (DLMO) is a commonly used circadian marker indicating the start time of evening melatonin synthesis in humans. Several quantitative techniques have…

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HypothesisSleep biologyMay 26

Links Between Epileptic Activity, Sleep Disruption and Mental Content During Sleep

Interactions between epilepsy and sleep are numerous and bidirectional. Sleep can facilitate epileptic activity and seizures in several syndromes, while sleep deprivation…

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HypothesisSleep biologyMay 26

TREAD: Time Restricted Eating Intervention for Alzheimer's Disease

The goal of this clinical trial is to learn if restricting the time of eating to allow for prolonged fasting at night may reduce sleep disturbances, cognitive decay, and pathology…

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