Sleep biology
Why we sleep — circadian rhythms and the glymphatic system
Sleep is when the brain self-cleans, the immune system consolidates, and memory is encoded. This topic curates the evidence on why sleep matters — biologically, not just behaviourally.
Low-dimensional population dynamics in the brainstem gate REM sleep
Rapid-eye-movement (REM) sleep is generated in the brainstem, but the brainstem population dynamics that drive transitions to REM sleep remain largely unknown. Here, combining mouse Neuropixels recordings and dimensionality reduction, we found that population activity in the midbrain and pons is dominated by two components, one of which captures strong infraslow fluctuations…
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3 articles in Sleep biology tagged Speculation, sorted by date
Enhancing Slow Wave Sleep in Depression
The goal of this pilot study is to determine if non-invasive brain stimulation during sleep can increase deep sleep in adults with depression. It will also determine if increased…
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Sleep, Light, Circadian, Central Oxidative Stress
Irregular sleep timing and sleep deficiency are pervasive in society despite evidence that sleep deficiency impairs cognition and is linked to neurodegenerative disease. Potential…
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